Yu Gui An Tang Pian 玉桂安糖片 GlucoBalance 301

方剂组成

• 肉桂（桂皮，Rou Gui / Cinnamomum cassia）
• 川黄连（Chuan Huang Lian / Coptis）
• 葛根（Ge Gen / Pueraria）
• 地骨皮（Di Gu Pi / Lycium root-bark）
• 麦冬（Mai Dong / Ophiopogon）
• 生地黄（Sheng Di Huang / Rehmannia）

传统功效与组方思路

• 清热燥湿，泻火解毒：以黄连为君，侧重清热降火；
• 温阳通脉，助运化：少佐肉桂，取其温中散寒、通行血脉之效；
• 解肌生津：葛根配伍麦冬、生地黄，共奏养阴生津、缓解口渴之功；
• 清虚热：地骨皮配生地黄，协同清退虚热、兼能凉血。

对应证候（参考）

• 阴虚内热或气阴两伤，兼有“热象”
• 常见表现：口渴喜饮、心烦、口干、便干；或餐后口渴、乏力
• 舌脉要点（参考）：舌红少津/苔薄黄，脉细数或滑数

现代药理研究

• 黄连：主要活性成分小檗碱（berberine）在多项研究中显示与调节葡萄糖代谢、改善胰岛素敏感性、影响炎症通路等相关；
• 肉桂：随机对照试验及Meta分析提示其可能有助于改善部分人群的空腹血糖与血脂指标，但现有结果尚存差异；
• 葛根：所含葛根素等成分与血管舒张、抗氧化作用相关；
• 麦冬与生地黄：现代研究多集中于其滋阴生津的药理机制与临床应用。
  

Formula Composition

• Cinnamon (Rou Gui / Cinnamomum cassia)
• Sichuan Coptis (Chuan Huang Lian / Coptis)
• Kudzu Root (Ge Gen / Pueraria)
• Wolfberry Root Bark (Di Gu Pi / Lycium root-bark)
• Dwarf Lilyturf Tuber (Mai Dong / Ophiopogon)
• Rehmannia Root (Sheng Di Huang / Rehmannia)
  

Traditional Functions and Formula Strategy

• Clear heat, dry dampness, purge fire, and detoxify: Coptis serves as the monarch herb, focusing on clearing heat and reducing fire.
• Warm yang, promote circulation, and assist transformation: A small amount of cinnamon is added to warm the middle, dispel cold, and facilitate blood vessel flow.
• Release muscle tension and generate fluids: Kudzu root combined with Dwarf Lilyturf Tuber and Rehmannia Root works to nourish yin, promote fluid production, and alleviate thirst.
• Clear deficiency heat: Wolfberry Root Bark paired with Rehmannia Root helps clear deficiency heat and cool the blood.
  

Corresponding Patterns (Reference)

• Yin deficiency with internal heat, or dual deficiency of qi and yin, accompanied by signs of "heat"
• Common symptoms: Thirst with desire to drink, irritability, dry mouth, dry stools; or postprandial thirst and fatigue
• Tongue and pulse indicators (reference): Red tongue with scanty moisture / thin yellow coating; thin and rapid or slippery and rapid pulse
  

Modern Pharmacological Research

• Coptis: Its primary active component, berberine, has been shown in multiple studies to be associated with regulating glucose metabolism, improving insulin sensitivity, and affecting inflammatory pathways.
• Cinnamon: Randomized controlled trials and meta-analyses suggest it may help improve fasting blood glucose and lipid profiles in certain populations, though current findings remain inconsistent.
• Kudzu Root: Contains compounds such as puerarin, which are associated with vasodilation and antioxidant effects.
• Dwarf Lilyturf Tuber & Rehmannia Root: Modern research focuses mainly on their pharmacological mechanisms and clinical applications in nourishing yin and promoting fluid production.