Geng Nian An Shen Pian 更年安神片 MenoPeace 302

方剂组成

• 熟地黄（Prepared Rehmannia Root）
• 山茱萸（Cornus Fruit）
• 山药（Chinese Yam）
• 知母（Anemarrhena Rhizome）
• 黄柏（Cork Tree Bark）
• 牡丹皮（Tree Peony Bark）
• 柴胡（Bupleurum Root）
• 女贞子（Glossy Privet Fruit）
• 旱莲草（Eclipta Herb）
• 酸枣仁（Spine Date Seed）
• 合欢花（Albizia Flower）
• 柏子仁（Chinese Arborvitae Kernel）
• 炙甘草（Honey-fried Licorice Root）

传统功效与组方思路

• 滋阴补肾、平衡阴阳：以熟地黄、山茱萸、山药、女贞子、旱莲草为主
• 清虚热、除烦：知母、黄柏、牡丹皮协同，侧重“滋阴降火”
• 疏肝解郁：柴胡配合欢花，助情志调畅
• 养心安神：酸枣仁、柏子仁、炙甘草合用，助眠宁心

对应证候（参考）

• 肝肾阴虚、虚火上扰；或阴虚兼有气郁
• 常见表现：潮热汗出、心烦易怒、失眠多梦、口干咽燥
• 舌脉要点（参考）：舌红少苔，脉细数

现代药理研究

• 酸枣仁：含多种活性成分，研究综述显示其具有助眠、抗焦虑样作用，并可调节神经递质与炎症通路。
• 知母：含知母皂苷等成分，其研究多围绕抗炎、神经系统调节等活性展开。
• 黄柏：研究报道显示其具有抗炎、抗菌等多种药理作用。
• 合欢花：现有研究涉及情绪调节与睡眠改善方向。
  

Formula Composition

• Prepared Rehmannia Root (Shu Di Huang)
• Cornus Fruit (Shan Zhu Yu)
• Chinese Yam (Shan Yao)
• Anemarrhena Rhizome (Zhi Mu)
• Cork Tree Bark (Huang Bai)
• Tree Peony Bark (Mu Dan Pi)
• Bupleurum Root (Chai Hu)
• Glossy Privet Fruit (Nu Zhen Zi)
• Eclipta Herb (Han Lian Cao)
• Spine Date Seed (Suan Zao Ren)
• Albizia Flower (He Huan Hua)
• Chinese Arborvitae Kernel (Bai Zi Ren)
• Honey-fried Licorice Root (Zhi Gan Cao)

Traditional Functions and Formula Strategy

• Nourishing kidney yin and balancing yin-yang: Primarily achieved with Prepared Rehmannia Root, Cornus Fruit, Chinese Yam, Glossy Privet Fruit, and Eclipta Herb.
• Clearing deficiency heat and relieving irritability: Coordinated use of Anemarrhena Rhizome, Cork Tree Bark, and Tree Peony Bark, emphasizing "nourishing yin and reducing fire."
• Soothing the liver and alleviating stagnation: Bupleurum Root paired with Albizia Flower to help regulate emotional state.
• Nourishing the heart and calming the mind: Combined use of Spine Date Seed, Chinese Arborvitae Kernel, and Honey-fried Licorice Root to improve sleep and tranquilize the heart.

Corresponding Patterns (Reference)

• Liver-kidney yin deficiency with ascending deficiency fire; or yin deficiency accompanied by qi stagnation.
• Common symptoms: Hot flashes, night sweats, irritability, insomnia, vivid dreaming, dry mouth and throat.
• Tongue and pulse indicators (reference): Red tongue with thin coating; thin and rapid pulse.

Modern Pharmacological Research

• Spine Date Seed: Contains multiple active components. Reviews indicate it has sleep-promoting, anxiety-reducing effects and can regulate neurotransmitter and inflammatory pathways.
• Anemarrhena Rhizome: Contains timosaponins and other components. Research focuses on anti-inflammatory and nervous system regulatory activities.
• Cork Tree Bark: Studies report anti-inflammatory, antibacterial, and various other pharmacological effects.
• Albizia Flower: Current research relates to mood regulation and sleep improvement.